Extravasation of non-chemotherapeutic drugs

Last Friday, while I was on my internal medicine/neurology rotation, I had the opportunity to help manage extravasation from mannitol.  Therefore, I thought this week we could review the treatment of extravasation of non-chemotherapy drugs.

What’s the most expensive medication in the world?

The American publishing and media company, Forbes, assembled a list of the world’s most expensive medications. They obtained the average medication price per patient per year by interviewing biotechnology industry experts and Wall Street analysts. According to Forbes, nine medications cost more than $200,000 per year. What are they?

Pharmacist Considerations for Continuous Renal Replacement Therapy

This week’s clinical pearl is a brief overview of the methods of continuous renal replacement therapy (CRRT), and the drug properties we should consider when deciding if dosing adjustments are necessary.


Understanding MELD by Sue Johanson, PharmD

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Corticosteroid: A Review by Rahel Woldo, Pharm.D.


Kidney Transplant Thymoglobulin Treatment Protocol

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Muromonab-CD3 (OKT-3) by Kimberly Fischer, RN BSN

Muromonab-CD3 is a mouse antibody produced from fusion of mouse plasma cells with human B-cell myeloma cells, targeting human T-cell CD-3. This mouse IgG2a was first approved in 1986 by FDA to be used in organ transplant rejection. It coats or binds CD-3, T-cell surface proteins, subjecting OKT-3/CD-3 complex to opsonization by the reticuloendothelial system in the liver with the first dose. The first dose of OKT-3 cause massive activation and subsequent depletion of oT-helper cells within the first day.

Kidney transplant Thymoglobulin Induction Protocol

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Pharmacist Guide to CMS Survey

Pharmacist Survival Guide for Center for Medicare & Medicaid Services (CMS) Visit for Transplant Program - A Colorado Experience
by Ike Kim, PharmD, BCPS

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